About Help FAQ

Symbol
Name
ID

Itgam
integrin alpha M
MGI:96607

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Thrombocytopenia	Asplenia	Hepatosplenomegaly
Disease(s) Associated with ITGAM	Thrombocytopenia	Asplenia	Hepatosplenomegaly
persistent fetal circulation syndrome
pre-eclampsia

Mouse Phenotypes

abnormal leukocyte migration

abnormal cellular extravasation

impaired leukocyte tethering or rolling

abnormal leukocyte adhesion

decreased T cell proliferation

impaired neutrophil phagocytosis

impaired hematopoiesis

decreased eosinophil cell number

increased eosinophil cell number

increased mean corpuscular hemoglobin

decreased neutrophil cell number

increased neutrophil cell number

abnormal neutrophil morphology

abnormal dendritic cell number

decreased CD11b-high dendritic cell number

increased plasmacytoid dendritic cell number

abnormal lymphocyte cell number

abnormal T cell subpopulation ratio

decreased CD4-positive, alpha-beta T cell number

increased CD8-positive, alpha-beta T cell number

decreased macrophage cell number

increased leukocyte cell number

abnormal neutrophil physiology

abnormal T cell activation

abnormal macrophage physiology

Availability

Mouse Genotype

Itgam^{em1(IMPC)Wtsi}/Itgam^{em1(IMPC)Wtsi}

Itgam^m1Btlr/Itgam^m1Btlr

Itgam^m2Btlr/Itgam^m2Btlr

Itgam^m3Btlr/Itgam^m3Btlr

Itgam^tm1Bll/Itgam^tm1Bll

Itgam^tm1Myd/Itgam^tm1Myd

Itgam^tm1Rws/Itgam^tm1Rws

Itgam^m1Btlr/Itgam⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23